There’s a good chance you already know this, but you should also avoid combining MDMA with other drugs. If you know you’re going to be mixing it with alcohol, don’t drink too much before your first dose, and make sure you keep track of how much you’re drinking while high. It’s unlikely that you’re going to get many of the positive effects out of alcohol once you’re rolling anyway, so if you’re only swigging the drinks out of habit then maybe just save your money. Hence, the most important thing to keep in mind when taking ecstasy is to always be circumspect.

  1. This can cause heart, liver, or kidney failure or even death.
  2. But if the authorities won’t provide information and tools for harm minimisation, we will.
  3. If you prefer video, watch this excellent video on How to use MDMA Safely on YouTube.
  4. There is evidence for use of betel nut in Timor, which dates some 13,000 years back, which is still in the use today, just to name one example.

This could mean cutting a tablet into quarters and only taking one at a time. It’s a lot safer to test your limits instead of diving right https://sober-house.org/ in. High doses of ecstasy can cause a spike in your body temperature. This can cause heart, liver, or kidney failure or even death.

What is MDMA (aka Ecstasy or Molly)?

Long-term MDMA use has been linked to a form of neurotoxicity that alters and impairs serotonin function in the brain. Unlike Ecstasy or Molly, pure MDMA has been proven sufficiently safe in clinical settings when taken a limited number of times in moderate doses. It’s also worth noting a 2010 study found MDMA to be among the least risky drugs to consumers and society as a whole. This can make using molly dangerous, and it can increase the risk of unpleasant effects.

In addition, common synthesis routes involve hazardous chemicals such as formaldehyde, ammonium chloride, and mercury. On the other hand, we can discuss on which the easiest drug to make money on is. Surely heroin or LSD have the highest profit, but are they the easiest to obtain? On the other hand, there are some cheaper things that are more easily being sold, like meth or MDMA. Or in the end, things that are the cheapest, like marijuana, but when sold on a regular basis, can make a decent profit.

This isn’t amnesia in the usual sense, just a complete loss of focus on what you were doing when something else comes up. Another significant danger is the fact that people who take ecstasy don’t really know what they are actually ingesting. It is important to note, however, that this research is still in the early stages.

One of the more colorful solutions has been baby pacifiers, which eventually became something of a fashion statement even among non-users at raves. Putting something between your front teeth lets you know when your jaw starts to close, allowing you to stop the gesture. Bruxism is mainly seen during the latter part of the ‘high’, and can be dealt with in a number of ways. An earlier version of ecstasy, MDMA became popular as a recreational drug during the 1960s and 1970s.

Convert Safrole to MDP2P

MDP2P, or 3,4-methylenedioxyphenyl-2-propanone, is an intermediate compound created in the synthesis of MDMA. It is typically made by the oxidation of safrole or its isomer isosafrole, but can also be prepared from piperonal, a widely used industrial chemical. Since MDP2P is on the DEA watch list similar to safrole, it has more recently been produced from a less-controlled precursor known as PMK glycidate. When refluxed with hydrochloric acid, PMK glycidate readily breaks down into MDP2P. Interestingly, some studies have shown that certain plants which contain high levels of nicotine, morphine, and cocaine have developed these levels through time in order to be eaten by herbivores less. Anyway, concerning human species, using psychoactive substances has a very long history.

👨‍⚕️ 1. Avoid MDMA if you have any of these pre-existing health conditions

These kits are essentially a litmus test for drugs, offering a rudimentary method of figuring out what a pill’s main ingredient is—whether it be ecstasy, meth, ketamine, or something else. By comparing this against the colour chart provided, you should be able to get some loose indication of the pill’s main ingredient. Buying from someone you know and trust is ideal, though not always possible. If you’re getting the ecstasy in the form of a pressed pill, you can usually find info about your particular pill on Pill Reports and do your research on what to expect according to some user-generated reviews. Short of that, and in lieu of more official pill testing services, you can take matters into your own hands and test the pills at home with an over-the-counter reagent testing kit.

Once the amalgam starts to bubble, the methylamine freebase and MDP2P solution are added, and the solution is allowed to reflux for several hours. The MDP2P undergoes a condensation reaction with methylamine, forming an imine that is reduced by the aluminum amalgam to MDMA. For several decades MDMA fell into obscurity, but its toxicity was briefly studied by the U.S. Army in the 1950s alongside other phenethylamines like mescaline. The first scientific paper published on MDMA appeared in 1960, when two Polish chemists reported a synthesis route. Later, Alexander Shulgin synthesized MDMA in 1965 and embarked on a series of self-experimentations.

What if I’m concerned about myself or a loved one’s use of MDMA?

Avoid driving or other activities that require mental sharpness until you’ve had a good night’s sleep. MDMA can continue to have lingering effects on your mental state for a day or two. In 2017, the Food and Drug Administration early signs of liver damage from alcohol granted MDMA breakthrough therapy status due to the preliminary evidence of its efficacy in the treatment of PTSD. This status helps expedite the development and review of substances for the treatment of serious conditions.

Some methylamine will escape the solution, which smells very bad (a bit like rotten fish) and isn’t healthy to breath in. While you can still find Molly in the club, these days, MDMA is experiencing a reinvention as a medicine for mental health disorders. Although the compound is currently classified as a Schedule I narcotic in the US, this designation looks set to change. In 2017, MAPS won breakthrough approval from the FDA for MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD). This temporary flooding of the brain with serotonin leads the consumer to experience the mood-elevating, stimulating, walking-on-clouds effects of the drug.

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